Oligodendrocytes are glial cells that myelinate neurons in the central nervous system (CNS). Oligodendrocyte progenitor cells (OPCs), which can divide and mature into oligodendrocytes, have small sensory organelles called primary cilia. Cilia are associated with several signaling pathways that control the generation of oligodendrocytes. One of these signaling pathways, the mTOR pathway, is important in the tuberous sclerosis complex, a genetic disease that causes seizures. Cilia restrain mTOR signaling, and it has been proposed that cilia defects lead to the marked upregulation of mTOR. My research aims to show to relationship between cilia, mTOR, and the TSC complex, show that defects in cilia lead to higher levels of mTOR, resulting in higher susceptibility to seizures in TSC, and to propose a treatment plan for TSC-related seizures.